Alithea Bio is ViVaTech Tech for Change winner 2026 and our CEO was recognized as one of Europe's rising stars by the Woman Tech EU award. We are a passionate startup with the vision of a world without cancer. Our mission is to democratize data for the development of efficient and safe immunotherapies. The company is growing and has more than 10 employees as of today, significant revenues and secured additional investment to drive our growth in coming years. We are working with many drug developers worldwide and contribute actively to bring next generation drugs to patients in need. Alithea has a laboratory in the BioCube in Berlin, Buch and state-of-the-art MS equipment.

Alithea’s main area of activity is the study of HLA-bound peptides by high sensitivity high resolution mass spectrometry (immunopeptidomics). The role of the proteomics/mass spectrometry scientist (F, M, D) will be to take responsibility over Alithea’s LC/MS equipment, develop PRM assays and maintain high quality performance through QC/QA procedures. Place of work is our laboratory in Berlin Buch.

Your role:

• Maintaining LC/MS hardware, cleaning ion optics, changing columns and repair MS and LC equipment as needed
• Develop and maintain QA/QC procedures to ensure compliance with quality standards
• Develop novel PRM assays for absolute quantification of peptide targets with synthetic peptides
• Evaluate new technologies and instruments to enhance our analytical capabilities, to improve workflow efficiency and outline a fit-for-future plan of the laboratory
• taking care of many other tasks in a small company from solvent waste management, backing up MS systems, presenting data to the team and managing stocks for MS consumables

Your profile:

• You have experience maintaining timsTOF mass spectrometers and different LC systems independently
• You are experienced in peptide mass spectrometry and high-throughput peptidomics/proteomics
• You are experienced in MS method development and data analysis, ideally using PRM
• You are passionate about immunopeptidomics
• You have experience implementing and working in quality controlled environments
• You have an analytical mindset, think out of the box and you are always challenging status quo
• You are independent and self-organized, experience with agile working methods a plus
• You are fluent in English, German is a plus

If you are interested in becoming a valuable member of a growing team in an innovative, interdisciplinary and diverse environment, we encourage you to contact us through info@alithea-bio.com. We are happy to receiving your application and are available to answer your questions.